Gastric secretions

Which substances, other than behaveal point, atomic number 18 hided by the stomach? pick up their secreted and physiological roles. oTwo main cannular secretors are present in the stomach mucosa: Oxyntic/ stomachic glands pyloric glands In addition, mucus-secreting cells line the entire surface of the stomach (surface mucous glands). These secrete large quantities of a very gummy mucus that coats the stomach mucosa with a gel class of mucus, very much more than 1mm thick. These glands provide a study shell of surety for the stomach wall and contri exclusivelye to lubrication of food transport. The mucus produced by these mucus-secreting cells is alkaline (thus the normal stomach wall is not clear to the highly acidic and proteolytic stomach secretions directly). oOxyntic/stomachal glands: Located on the inside surfaces of the body and fundus of the stomach pay the proximal 80% of the stomach A typical gland is composed of 3 types of cells: mucous neck cel ls which secrete in the first place mucus; peptic/chief cells which secrete large quantities of pepsinogen; parietal/oxyntic cells which secrete hydrochloric acid (gastric acid) and intrinsic factor oPyloric glands: Are dictated in the antral portion of the stomach Make up the distal 20% of the stomach resign mainly mucus for certificate of the pyloric mucosa from gastric acid; in addition secrete the hormone gastrin and a mid stick amount of pepsinogen oPepsinogen: Secreted mainly by peptic cells of the oxyntic glands, but a small amount is also secreted from the mucous cells of the oxyntic glands and from the pyloric glands (function is the same) Molecular weight = c. 42,500 Da Is unemployed when first secreted into the into the stomach Is activated to plaster cast pepsin: during this process, pepsinogen is sunder into a 35,000 Da molecule (pepsin) HCl creates an acidic purlieu which allows pepsinogen to unfold and divide itself in an autocatalytic fashion, thereby generating pepsin Pepsin acts as an! ...If you want to get a full essay, order it on our website: OrderCustomPaper.com

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